Perinatal predictors of clinical instability at birth in late-preterm and term infants

Georgia A Santomartino; Douglas A Blank; Alissa Heng; Anthony Woodward; Stefan C Kane; Marta Thio; Graeme R Polglase; Stuart B Hooper; Peter G Davis; Shiraz Badurdeen

Journal article

Perinatal predictors of clinical instability at birth in late-preterm and term infants

Georgia A Santomartino, Douglas A Blank, Alissa Heng, Anthony Woodward, Stefan C Kane, Marta Thio, Graeme R Polglase, Stuart B Hooper, Peter G Davis, Shiraz Badurdeen

EUROPEAN JOURNAL OF PEDIATRICS | SPRINGER | Published : 2023

DOI: 10.1007/s00431-022-04684-5

Abstract

To identify characteristics associated with delivery room clinical instability in at-risk infants. Prospective cohort study. Two perinatal centres in Melbourne, Australia. Infants born at ≥ 35+0 weeks’ gestation with a first-line paediatric doctor requested to attend. Clinical instability defined as any one of heart rate < 100 beats per minute for ≥ 20 s in the first 10 min after birth, maximum fraction of inspired oxygen of ≥ 0.70 in the first 10 min after birth, 5-min Apgar score of < 7, intubated in the delivery room or admitted to the neonatal unit for respiratory support. Four hundred and seventy-three infants were included. The median (IQR) gestational age at birth was 39+4 (38+4—40+4)..

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University of Melbourne Researchers

Stefan Kane Author

Marta Thio Author

Peter Davis Author

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Grants

Awarded by National Health and Medical Research Council (NHMRC)

Funding Acknowledgements

Open Access funding enabled and organized by CAUL and its Member Institutions. This study was supported by the National Health and Medical Research Council (NHMRC) through a Programme Grant (#606789) and Fellowships (SBH: APP545921, GRP: APP1105526, PGD: APP1059111). SB is supported by an Australian Government Research Training Program Scholarship.